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A team of five experts with extensive experience in acne conducted a literature review of the main scientific evidence and met to discuss the best practices and personal experiences to develop a guide containing recommendations for the clinical practice of adult female acne.

Although most AFA patients show no signs of clinical or laboratory hyperandrogenism, slightly elevated levels of S-DHEA have been observed. 41

103. Dreno B, Castell A, Tsankov N, Lipozencic J, Serdaroglu S, Gutierrez V, et al. Interest of the association retinaldehyde/glycolic acid in adult acne. J Eur Acad Dermatol Venereol. 2009; 23 :529–532. [PubMed] [Google Scholar]

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Adult female acne: a guide to clinical practice*

Acne can make someone feel unhappy about their appearance, develop poor self-esteem and not want to be around other people.

65. de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, et al. Combined oral contraceptives: venous thrombosis. Cochrane Database Syst Rev. 2014:CD010813. [PMC free article] [PubMed] [Google Scholar]

When your oil glands go into overdrive, your pores can get clogged, causing acne. Fortunately, these scientific strategies can help you tame breakouts.

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The application of blue or red light emitting diodes (LEDs) has an anti-inflammatory effect faster than topical and/or systemic treatments. One study showed that this effect was similar to salicylic acid peel. The associated lights in the early stages of treatment improved inflammation and adhesion. No adverse event has been recorded. 112 Photodynamic Therapy (PDT), as it is better known, has been proposed as a therapeutic option for acne, although with many doubts and scanty evidence. 113

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Stress

The efficacy and safety of adapalene 0.1% combined with 2.5% benzoyl peroxide gel compared to the vehicle in women 25 years of age or older were analyzed by meta-analysis of data extracted from subgroups from three multi-center, phase 2 and 3, randomized, parallel and double-blind studies. A rapid onset of action was demonstrated, with a significant reduction in lesions from the first week of use; the combination was considered effective, safe and tolerated well in both the population under 18 years and over 25 years, with similar indices. 46

5 Department of Dermatology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP), Brazil.

The Difference Between Male & Female Acne

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There is an abnormal proliferation of keratinocytes, stimulated by pro-inflammatory cytokines, such as interleukin-1 alpha (IL-1 alpha). This cytokine is triggered by the activation of Toll-like receptors or TLR 2 and 4, related to innate immunity, which recognize molecular patterns present in P. acnes, as well as sebaceous hypersecretion and squalene peroxidation. 14 The formation of the micro-comedone is also preceded by a mononuclear infiltrate formed mainly by CD4+ T lymphocytes and CD68+ macrophages, which corroborates to the hypothesis of the participation of the inflammatory process in the early stages of acne. 22

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Conclusion

104. Monfrecola G, Cacciapuoti S, Capasso C, Delfino M, Fabbrocini G. Tolerability and camouflaging effect of corrective makeup for acne: results of a clinical study of a novel face compact cream. Clin Cosmet Investig Dermatol. 2016; 9 :307–313. [PMC free article] [PubMed] [Google Scholar]

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56. Dréno B, Bettoli V, Ochsendorf F, Layton AM, Perez M, Dakovic R. Efficacy and safety of clindamycin phosphate 1.2%/tretinoin 0.025% formulation for the treatment of acne vulgaris: pooled analysis of data from three randomised, double-blind, parallel-group, phase III studies. Eur J Dermatol. 2014; 24 :201–209. [PubMed] [Google Scholar]

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Inhibitors of ovarian androgen production

Studies related to acne point to a negative influence on quality of life, including the presence of signs and symptoms of depression and anxiety, such as anger and low self-esteem. 125-127 The use of disease-specific questionnaires, such as Quality of Life in Acne (Acne-QoL), already translated and validated for Brazilian Portuguese, quantifies the impact of acne on quality of life. 128-130

Hormonal changes related to birth control pills, menstrual periods, and pregnancy can trigger acne. Other external acne triggers include heavy face creams and cosmetics, hair dyes, and greasy hair ointment — all of which can increase blockage of pores.

7 Dos and Don’ts for Treating Teen Acne

According to the American Academy of Dermatology Association, you can thank your fluctuating hormones for these outbreaks. These fluctuations increase the amount of sebum produced in your skin.

Your GP may refer you to a dermatologist (a skin specialist) if your acne is severe and they can help you decide which treatment is best for you.

The type of makeup you opt for also matters. “These days, most makeup brands are acne-friendly. The words to look for are ‘noncomedogenic’ and ‘oil-free,’” says Brantley. Some makeup options include flesh-tinted lotions to hide pimples and powder over an oil-free foundation.

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Beatriz Medeiros Ribeiro

21. Albuquerque RG, Rocha MA, Bagatin E, Tufik S, Andersen ML. Could adult female acne be associated with modern life? Arch Dermatol Res. 2014; 306 :683–688. [PubMed] [Google Scholar]

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Cysts: Deep, pus-filled pimples.

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